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While "internal state" or impulsivity are terms more generally discussed in psychology or neuroscience, the concept is familiar to anyone. Sleep is not a uniform state of being. (b) Heroin is cooked on a spoon over a candle. In addition, if a pregnant woman consumes alcohol, her infant may be born with a cluster of birth defects and symptoms collectively called fetal alcohol spectrum disorder (FASD) or fetal alcohol syndrome (FAS). In the brain, the hypothalamus, which lies above the pituitary gland, is a main center of homeostasis. It seems like everyone knows a friend, family member, or neighbor who has died of an overdose. Stage 3is often referred to as deep sleep or slow-wave sleep because this stage is characterized by low frequency (less than 3 Hz), high amplitudedelta waves(Figure 4.10). Typically, individuals suffering from night terrors will fall back asleep again within a short time. Loss of appetite. A person who has a substance use disorder often uses more of the substance than they originally intended to and continues to use that substance despite experiencing significant adverse consequences. Vaping uses battery-powered devices, sometimes called e-cigarettes, that deliver liquid nicotine and flavorings as a vapor. Many of these processes, like much of psychological behavior, are rooted in our biology. That includes exercise and bright light from devices. Our experiences change dramatically while we are in deep sleep and once again when we are dreaming. Research indicates that included among these possible benefits are increased capacities for creative thinking (Cai, Mednick, Harrison, Kanady, & Mednick, 2009; Wagner, Gais, Haider, Verleger, & Born, 2004), language learning (Fenn, Nusbaum, & Margoliash, 2003; Gmez, Bootzin, & Nadel, 2006), and inferential judgments (Ellenbogen, Hu, Payne, Titone, & Walker, 2007). Sleep is characterized by certain patterns of activity of the brain that can be visualized using electroencephalography (EEG), and different phases of sleep can be differentiated using EEG as well. Avoid anything stimulating for an hour before bed. the ability to spend time, good time with them when youre not feeling absolutely exhausted . These symptoms include fatigue, sluggishness, irritability, andinsomnia(i.e., a consistent difficulty in falling or staying asleep for at least three nights a week over a months time) (Roth, 2007). The participant is told to be open to the process of hypnosis, trust the hypnotist and let go. The participant is guided to focus on one thing, such as the hypnotists words or a ticking watch. Furthermore, these types of behaviors ultimately disrupt sleep, although affected individuals have no memories that these behaviors have occurred (Arnulf, 2012). While opioid withdrawal can be extremely unpleasant, it is not life-threatening (Julien, 2005). The brain waves associated with REM sleep, outlined in the red box in (a), look very similar to those seen (b) during wakefulness. One hypothesis from this perspective might argue that sleep is essential to restore resources that are expended during the day. Often, however, people wishing to learn to meditate receive some training in techniques to achieve a meditative state. However, when a stimulant drug was used in conjunction with a popular antidepressant, her condition improved dramatically. Is it absolutely essential that we sleep? Heavy meals may make you sleepy, but they can also lead to frequent awakenings due to gastric distress. Rather, the ISS r ecognizes mixed states and depressive symptoms during manic and hypomanic episodes. Methamphetamineis a type of amphetamine that can be made from ingredients that are readily available (e.g., medications containing pseudoephedrine, a compound found in many over-the-counter cold and flu remedies). The decade from 20102019 brought many changes in laws regarding marijuana. Variations and adaptations in cognition and behavior make individuals more or less successful in reproducing and passing their genes to their offspring. Historically, heroin has been a major opioid drug of abuse (Figure 4.17). It is not uncommon for people suffering from undiagnosed or untreated sleep apnea to fear that their careers will be affected by the lack of sleep, illustrated by this statement from another patient, Im in a job where theres a premium on being mentally alert. For example, withdrawal from sedative drugs often produces unpleasant arousal and agitation. The clock sets itself with light information received through projections from the retina. (credit a: modification of work by Todd Huffman), Psychedelic images like this are often associated with hallucinogenic compounds. These individual differences in circadian patterns of activity are known as a persons chronotype, and research demonstrates that morning larks and night owls differ with regard to sleep regulation (Taillard, Philip, Coste, Sagaspe, & Bioulac, 2003). Our lives involve regular, dramatic changes in the degree to which we are aware of our surroundings and our internal states. Historically, somnambulism has been treated with a variety of pharmacotherapies ranging from benzodiazepines to antidepressants. (credit: modification of work by new 1lluminati/Flickr), Medical marijuana shops are becoming more and more common in the United States. One important regulator of sleep-wake cycles is the hormonemelatonin. Generally, treatment for night terrors is unnecessary unless there is some underlying medical or psychological condition that is contributing to the night terrors (Mayo Clinic, n.d.). Participants were told they would not feel pain, but they could press a button if they did; while they reported not feeling pain, they did, in fact, press the button, suggesting a dissociation of consciousness while in the hypnotic state (Hilgard & Hilgard, 1994). Whilecaffeineis generally considered a relatively safe drug, high blood levels of caffeine can result in insomnia, agitation, muscle twitching, nausea, irregular heartbeat, and even death (Reissig, Strain, & Griffiths, 2009; Wolt, Ganetsky, & Babu, 2012). All of the following are true statements concerning the health of Americans EXCEPT: a. mortality rates from smoking have declined. An agonist facilitates the activity of a neurotransmitter system, and antagonists impede neurotransmitter activity. The FDAs 2013 recommendation for tighter controls on opiate prescriptions left many patients addicted to prescription drugs like OxyContin unable to obtain legitimate prescriptions. If people are deprived of REM sleep and then allowed to sleep without disturbance, they will spend more time in REM sleep in what would appear to be an effort to recoup the lost time in REM. Causes. that would be one of the problems that Ive encountered. Physical dependenceinvolves changes in normal bodily functionsthe user will experience withdrawal from the drug upon cessation of use. In 2012, Kromann and Nielson reported on a case study of a 40-year-old woman who suffered significant ill effects from her use of caffeine. The participant is made comfortable and is directed to be relaxed and sleepy. While cognitive deficits may be the most obvious, many body systems are negatively impacted by lack of sleep. There is a trend that females report more somatic symptoms than males; thus, more females are diagnosed with somatic symptom disorder than males (APA, 2022). While many users snort cocaine, intravenous injection and inhalation (smoking) are also common. Central sleep apnea is caused by a failure of the brain to activate the muscles of breathing during sleep. Obstructive sleep apneaoccurs when an individuals airway becomes blocked during sleep, and air is prevented from entering the lungs. Opioid addiction reached crisis levels in the United States such that by 2019, an average of 130 people diedeach dayof an opioid overdose (NIDA, 2019). While awake, we feel alert and aware of the many important things going on around us. Users can experience physical symptoms that include nausea, elevated blood pressure, and increased heart rate. In addition to withdrawal, many individuals who are diagnosed with substance use disorders will also develop tolerance to these substances. As you have learned, drugs can act as agonists or antagonists of a given neurotransmitter system. Sleep deprivation, in general, is associated with a number of negative consequences (Brown, 2012). Increased alertness, mild euphoria, decreased appetite in low doses. (credit sleeping: modification of work by Ryan Vaarsi). Aches and pains, such as severe headache and muscle and joint pain. Mescaline and LSD are serotonin agonists, and PCP (angel dust) and ketamine (an animal anesthetic) act as antagonists of the NMDA glutamate receptor. Insleepwalking, or somnambulism, the sleeper engages in relatively complex behaviors ranging from wandering about to driving an automobile. The average EVD case fatality rate is around 50%. In fact, abuse of prescription opioid medications is becoming a major concern worldwide (Aquina, Marques-Baptista, Bridgeman, & Merlin, 2009; Casati, Sedefov, & Pfeiffer-Gerschel, 2012). The heart rate slows . Recommendations like these have helped to decrease the number of infant deaths from SIDS in recent years (Mitchell, 2009; Task Force on Sudden Infant Death Syndrome, 2011). The term was first coined by a physiologist named Walter Cannon in 1926. Awareness of internal stimuli includes feeling pain, hunger, thirst, sleepiness, and being aware of our thoughts and emotions. While we all experience altered states of consciousness in the form of sleep on a regular basis, some people use drugs and other substances that result in altered states of consciousness as well. Awareness of external stimuli includes experiences such as seeing the light from the sun, feeling the warmth of a room, and hearing the voice of a friend. For instance, the concentration of various ions in your blood must be kept steady, along with pH and the concentration of glucose. Adepressantis a drug that tends to suppress central nervous system activity. For example, a person may work from 7:00 a.m. to 3:00 p.m. on Monday, 3:00 a.m. to 11:00 a.m. on Tuesday, and 11:00 a.m. to 7:00 p.m. on Wednesday. Stimulant users seek aeuphoric high, feelings of intense elation and pleasure, especially in those users who take the drug via intravenous injection or smoking. Narcolepsy is associated with reduced levels of the signaling molecule hypocretin in some areas of the brain (De la Herrn-Arita & Drucker-Coln, 2012; Han, 2012), and the traditional stimulant drugs do not have direct effects on this system. Anopioidis one of a category of drugs that includes heroin, morphine, methadone, and codeine. Body temperature rises throughout the waking day, peaking in the afternoon, and falls during sleep with the lowest point occurring during the very early morning hours. Some of these approaches, such as using a bright light as shown inFigure 4.4, have been shown to alleviate some of the problems experienced by individuals suffering from jet lag or from the consequences of rotating shift work. There may also be differences in both brain structure and function in infants that die from SIDS (Berkowitz, 2012; Mage & Donner, 2006; Thach, 2005). A womans menstrual cycle is an example of a biological rhythma recurring, cyclical pattern of bodily changes. For instance, if a woman dreams about being chased by a snake, Freud might have argued that this represents the womans fear of sexual intimacy, with the snake serving as a symbol of a mans penis. Thepineal gland, an endocrine structure located inside the brain that releases melatonin, is thought to be involved in the regulation of various biological rhythms and of the immune system during sleep (Hardeland, Pandi-Perumal, & Cardinali, 2006). These brain areas include the prefrontal cortex and basal ganglia. Beyond being awake or asleep, there are many other states of consciousness people experience. In the wake of the opiate epidemic, many drug cartels in Mexico are shifting from producing heroin to producing highly potent but inexpensive forms of methamphetamine. There is a tremendous amount of variability among sufferers, both in terms of how symptoms of narcolepsy manifest and the effectiveness of currently available treatment options. The crisis actually began in the 1990s, when pharmaceutical companies began mass-marketing pain-relieving opioid drugs like OxyContin with the promise (now known to be false) that they were non-addictive. Generally, people use caffeine to maintain increased levels of alertness and arousal. Like many other stimulants, cocaine agonizes the dopamine neurotransmitter system by blocking the reuptake of dopamine in the neuronal synapse. Although she did not experience any dream-like hallucinations, she was diagnosed with narcolepsy as a result of sleep testing. Sleep apnea is defined as a reduction or cessation of breathing during sleep. In this section, we will discuss each of these stages of sleep and their associated patterns of brain wave activity. Freud made distinctions between the manifest content and the latent content of dreams. His children and his wifes parents all agreed that Falater had an excellent relationship with his wife and they couldnt think of a reason that would provide any sort of motive to murder her (Cartwright, 2004). It was getting to the point where it was kind of scary (Henry & Rosenthal, 2013, p. 52). During sleep, the pituitary gland secretes both FSH and LH which are important in regulating the reproductive system (Christensen et al., 2012; Sofikitis et al., 2008). Sleep is also associated with the secretion and regulation of a number of hormones from several endocrine glands including: melatonin, follicle stimulating hormone (FSH), luteinizing hormone (LH), and growth hormone (National Institutes of Health, n.d.).

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